Mechanistic Studies of Reactions of Alkaytion of Schiffs Bases

Abstract

The Schiff's Bases (N-arylidene benzylamines) (1-10) had been alkylated with different alkyl halides by applying solid-liquid phase-transfer catalysis system (solid K₂CO₃, CH₃CN, TBAB). To form the corresponding alkylated products (11-39) The products were identified as the corresponding alkylated Schiff's bases, by analyses of their spectral data (UV,IR,NMR,MS). The mechanism of the reaction was investigated on the basis of theoretical approach using semi-empirical AM1 module in the CS ChemOffice molecular modeling package.