The role of Vitamin D deficiency in patients with Diabetic Foot Ulcer

Abstract

The aim of this study is identification the relationship between vitamin D deficiency in the diabetic foot ulcer patient and the aerobic bacterial types, because it's, with know their resistance to some antibiotics used. The present study was cross sectional type which carried out from 12th of August 2019 to 25th of February 2020 in Salah al-Din Governorate. Seventy patients suffered from DM presented with diabetic foot ulcer (41 male and 29 female), blood sample was drawn and taken swab from foot ulcer by swab transport media and send to the lab. We found the high significant ratio in decrease blood serum concentration (p≤0.01) of vitamin D in persons with diabetic foot and in persons with diabetes compared with the control group. Also, we found high significant level at (p≤0.01) in the number of patients with DM and DFU for males compared to females and (87%) patients with DFU had a bacterial infection, in addition, the poly-microbial infection was (60.7%) case more than single microbial infection (39.3%), plus showed that the infection with positive bacteria (58.7%) was more than negative bacteria (41%). The highest rate of bacterial infection in DFU was recorded for S. aureus (36.7%), while S. ficaria was the only cause of infection, and it was isolated (0.9%). Most of bacterial isolates that cause DFU were resistant to the antibiotics used except for Levofloxacin, which most bacteria were sensitive, while bacteria were resistance to carbincillin (100%).