Evaluation of Circulation Levels of ASA and IL-6 in Infertile Men

Abstract

The elevated levels of ASA and IL-6 antibodies in semen have a fundamental role in immune sterility, so the current study was designed to compare the blood serum levels of these markers between infertile and healthy men. Serum levels of ASA and IL-6, of 46 infertile and 44 fertile males were assessed using ELISA test (standard curve). The findings showed that mean serum IL-6 and ASA levels were significantly higher in infertile male compared with control (107.4 pg/ml, and 51.4 U/ml, VS 8.3 pg/ml, 11.50 U/ml at P≤ 0.01). According to the types of infertility the result also showed there was a significant statistically difference in the level of IL-6, and ASA within comparted groups. These data concluded that the significant increase in serum ASA and IL-6, compared to the lower levels in the control, indicating that these markers may be implicated in the pathogenesis of male infertility.